Hugo Cerecetto Selected Research

Triose-Phosphate Isomerase (Triosephosphate Isomerase)

3/2018	Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment.
1/2016	Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.
4/2014	New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors: a deeper insight into the mechanism of inhibition.
10/2013	1,2,4-thiadiazol-5(4H)-ones: a new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibition.

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Hugo Cerecetto Research Topics

Disease

32	Chagas Disease (American Trypanosomiasis) 12/2022 - 11/2002
26	Neoplasms (Cancer) 01/2024 - 04/2004
13	Hypoxia (Hypoxemia) 01/2017 - 05/2005
5	Glioma (Gliomas) 01/2023 - 07/2017
5	Neglected Diseases 05/2014 - 06/2009
4	Infections 01/2024 - 01/2012
4	African Trypanosomiasis (Nagana) 02/2021 - 05/2011
3	Glioblastoma (Glioblastoma Multiforme) 01/2023 - 11/2020
3	Carcinogenesis 01/2020 - 01/2015
2	Fascioliasis 12/2023 - 06/2019
2	COVID-19 01/2023 - 01/2023
2	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2017
2	Breast Neoplasms (Breast Cancer) 12/2021 - 06/2016
2	Melanoma (Melanoma, Malignant) 10/2021 - 01/2017
2	Multiple Myeloma 01/2021 - 01/2017
2	Inflammation (Inflammations) 01/2020 - 11/2018
2	Atherosclerosis 11/2018 - 01/2014
2	Hepatocellular Carcinoma (Hepatoma) 11/2015 - 01/2015
2	Leishmaniasis 05/2011 - 09/2008
2	Parasitic Diseases (Parasitic Disease) 12/2010 - 12/2009
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2008 - 10/2005
1	Atopic Dermatitis (Atopic Eczema) 01/2024
1	Glutaric Acidemia I 05/2023
1	Lymphoma (Lymphomas) 02/2023
1	Necrosis 01/2023
1	Skin Neoplasms (Skin Cancer) 10/2021

Drug/Important Bio-Agent (IBA)

12	LigandsIBA 01/2017 - 04/2004
7	NifurtimoxIBA 08/2015 - 01/2008
6	EnzymesIBA 01/2016 - 04/2013
5	ProdrugsIBA 12/2021 - 08/2006
5	phenazine FDA Link 07/2019 - 09/2008
5	Cytotoxins (Cytolysins)IBA 01/2011 - 05/2005
4	benzonidazole (benznidazole)IBA 03/2018 - 06/2010
4	Triose-Phosphate Isomerase (Triosephosphate Isomerase)IBA 03/2018 - 10/2013
4	MetalsIBA 09/2013 - 04/2004
4	RadiopharmaceuticalsIBA 02/2013 - 02/2006
4	ThiosemicarbazonesIBA 12/2009 - 09/2004
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2023 - 01/2019
3	Antiviral Agents (Antivirals)IBA 01/2023 - 01/2020
3	Sunitinib (Sutent)FDA Link 01/2023 - 11/2020
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2017
3	salicylaldehydeIBA 06/2015 - 02/2005
3	SemicarbazonesIBA 06/2015 - 02/2005
3	OxidesIBA 01/2014 - 02/2009
3	4-nitroimidazoleIBA 02/2013 - 01/2011
2	TriclabendazoleIBA 12/2023 - 01/2016
2	ChalconesIBA 12/2023 - 05/2007
2	BoronIBA 01/2023 - 07/2017
2	favipiravirIBA 01/2023 - 01/2023
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2023 - 07/2017
2	Lapatinib (GW572016)FDA Link 01/2023 - 01/2020
2	MicellesIBA 12/2021 - 12/2021
2	Biomarkers (Surrogate Marker)IBA 12/2021 - 10/2021
2	tocilizumab (atlizumab)FDA Link 01/2021 - 01/2017
2	Phosphotransferases (Kinase)IBA 11/2020 - 07/2017
2	Tyrosine (L-Tyrosine)FDA Link 11/2020 - 01/2017
2	anilinoquinazolineIBA 03/2018 - 07/2017
2	Thomsen-Friedenreich antibodiesIBA 03/2018 - 03/2015
2	Antineoplastic Agents (Antineoplastics)IBA 06/2016 - 05/2006
2	TransferasesIBA 11/2015 - 01/2015
2	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA 11/2015 - 01/2015
2	Aryl Hydrocarbon Receptor Nuclear TranslocatorIBA 11/2015 - 01/2015
2	ThiazolesIBA 07/2015 - 03/2015
2	VanadiumIBA 06/2015 - 02/2005
2	CarcinogensIBA 01/2015 - 07/2010
2	benzofuroxanIBA 01/2014 - 12/2005
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2012 - 07/2011
2	Metronidazole (Metric)FDA LinkGeneric 07/2012 - 01/2011
2	Coordination ComplexesIBA 06/2012 - 12/2010
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 12/2009 - 04/2004
2	Tirapazamine (SR 4233)IBA 02/2009 - 08/2006
2	PlatinumIBA 06/2008 - 05/2008
2	PalladiumIBA 06/2008 - 06/2006
1	Boronic AcidsIBA 01/2024
1	AnthelminticsIBA 12/2023
1	VaccinesIBA 12/2023
1	CathepsinsIBA 12/2023
1	Immune Checkpoint ProteinsIBA 05/2023
1	glutaric acidIBA 05/2023
1	Dasatinib (BMS 354825)FDA Link 02/2023
1	FITC-annexin A5IBA 01/2023
1	DAPIIBA 01/2023
1	Choline (Choline Chloride)IBA 01/2023
1	peptide permeaseIBA 01/2023
1	RNA (Ribonucleic Acid)IBA 01/2023
1	Liposomes (Liposome)IBA 01/2023
1	Drug CombinationsIBA 12/2022
1	Glycogen Synthase Kinase 3IBA 01/2022
1	Glycogen Synthase (Synthase I)IBA 01/2022
1	maleimideIBA 01/2022
1	Fluorescent Dyes (Fluorescent Probes)IBA 10/2021
1	Nucleotide AptamersIBA 10/2021
1	Tumor Biomarkers (Tumor Markers)IBA 10/2021
1	CoumarinsIBA 01/2021

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 02/2023 - 11/2002
6	Therapeutics 01/2020 - 06/2010
3	Boron Neutron Capture Therapy 01/2023 - 01/2019
2	Radiotherapy 11/2020 - 02/2013
2	Chemoprevention 04/2016 - 01/2015
1	Injections 10/2021